Vitro 3D Drug Sensitivity Detection of Micro Tumor (PTC) Combined with Tumor Whole Exon (WES) Sequencing Technology to Guide Postoperative Adjuvant Treatment Strategy and Prognosis of Colorectal Cancer

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The research objectives is to compare vitro 3D drug sensitivity test results of micro tumor (PTC) with the clinical outcomes of patients, evaluate the consistency between the test results of the technology platform and the clinical prognosis, and explore the decision-making value and guiding significance of this technology in assisting the precise treatment of colorectal cancer. The completion of this study will provide real-world data support for the clinical application of micro tumor (PTC) in vitro 3D drug sensitivity detection technology, and provide more valuable reference basis for realizing the individualization and accuracy of colorectal cancer treatment and improving the clinical benefit rate.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

⁃ Age 18 \

• 75 years old, regardless of gender

⁃ Patients with colorectal cancer diagnosed by histopathology or cytology

⁃ Colorectal cancer patients who need adjuvant therapy after radical surgery and have not received neoadjuvant therapy

⁃ Having at least one assessable tumor focus

⁃ ECoG physical condition score ≤ 2 points

⁃ Voluntarily participate and sign informed consent

Locations
Other Locations
China
Peking Union Medical College Hospital
RECRUITING
Beijing
Contact Information
Primary
Guole Lin
linguole@126.com
13801081483
Time Frame
Start Date: 2021-09-01
Estimated Completion Date: 2027-09-01
Participants
Target number of participants: 200
Treatments
Experimental: PTC test group
The adjuvant chemotherapy scheme was selected according to the 3D drug sensitivity test results of micro tumor (PTC) in vitro
No_intervention: control group
Making adjuvant chemotherapy strategy based on clinical experience
Related Therapeutic Areas
Sponsors
Leads: Peking Union Medical College Hospital

This content was sourced from clinicaltrials.gov

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